HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indene-1-carboxylic acid, 2,3-dihydro-3-oxo- → 1H-Indene-1-carboxylic acid, 2,3-dihydro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indene-1-carboxylic acid, 2,3-dihydro-3-oxo- | HCID 99815 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1H-Indene-1-carboxylic acid, 2,3-dihydro- | HCID 85728 | 95% |
Reaction Steps
A MeOH (1 mL) solution of 3-oxo-indancarboxylic acid (85.5 mg, 0.485 mmol) was mixed with Pd/C (16.5 mg) and hydrogenated at room temperature under 55 psi H2 pressure for 18 h. The crude mixture was filtered and concentrated to give 1-indanecarboxylic acid (74.4 mg, 95%). MS Found: (M−H)−=161.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324401B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-d0bd6ccfb39142699fd2818d650c0820 |
| Source note | uspto-grants-2012_12 |