4-Phenoxyphenylboronic acid → 4-Hydroxy-2-oxo-6-(4-phenoxy-phenyl)-2H-chromene-3-carboxylic acid methyl ester

HRID 2190904Notes

Reaction equation

HRID 2190904 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:17])[O:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][C:11](Br)=[CH:10][CH:9]=2)=[O:4].[O:18]([C:25]1[CH:30]=[CH:29][C:28](B(O)O)=[CH:27][CH:26]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:17])[O:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][C:11]([C:28]1[CH:29]=[CH:30][C:25]([O:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:26][CH:27]=1)=[CH:10][CH:9]=2)=[O:4]

Participants

3

Reactant 2

HCID 27343774-Phenoxyphenylboronic acidHCID 866494596-bromo-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester

Product 1

HCID 866494604-Hydroxy-2-oxo-6-(4-phenoxy-phenyl)-2H-chromene-3-carboxylic acid methyl ester

Procedure

4-Hydroxy-2-oxo-6-(4-phenoxy-phenyl)-2H-chromene-3-carboxylic acid methyl ester was prepared from 6-bromo-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester and 4-phenoxyphenylboronic acid under conditions analogous to example 3-a. MS ESI(+) m/e: 389 (M+1).

Sources & evidence

ORD record
ord-2433091052034da7be4faf1587a5a0de
Source dataset
uspto-grants-2012_12
Patent number
US08324405B2

Reaction notes

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