HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyloxy-phenylboronic acid → 6-(4-Benzyloxy-phenyl)-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyloxy-phenylboronic acid | HCID 2734314 | — |
| Reactant | 6-bromo-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester | HCID 86649459 | — |
| Product | 6-(4-Benzyloxy-phenyl)-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester | HCID 86649462 | — |
Reaction Steps
6-(4-Benzyloxy-phenyl)-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester was prepared from 6-bromo-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester (example 2-b) and 4-benzyloxyphenylboronic acid under conditions analogous to example 3-a. 1H NMR (200 MHz, CDCl3): δ (ppm)=8.14 (d, J=2.3 Hz, 1H), 7.85 (dd, J=8.5, 2.3 Hz, 1H), 7.54-7.08 (m, 10H), 5.12 (s, 2H), 4.04 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324405B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-407cf56d9ee44c4c8b2e706cba2cd19d |
| Source note | uspto-grants-2012_12 |