Sodium Glycinate → HCID 54746549, compound

Participants

Reaction Steps

A mixture of 6,8-dichloro-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester (400 mg, 1.39 mmol) and glycine sodium salt (674 mg, 6.94 mmol) in 2-methoxyethanol (14 mL) was heated to reflux overnight. Reaction mixture was concentrated and dissolved in water (100 mL). The solution was acidified by 1 N aq HCl to pH=2-3. White precipitate was collected, rinsed with water and methanol and dried to give the title compound (401 mg). MS ESI(−) m/e: 332, 330 (M−1).

Provenance & Evidence