Tetramethyltin → HCID 86649469, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of [(7-bromo-4-hydroxy-2-oxo-2H-chromene-3-carbonyl)-amino]-acetic acid ethyl ester (212 mg, 0.563 mmol), tetramethyltin (0.158 mL, 1.14 mmol) and Pd(PPh3)2Cl2 (20 mg, 0.029 mmol) in N,N-dimethylformamide (2 mL) was heated in a 120° C.-oil bath under nitrogen for 1 h; then cooled, diluted with ethyl acetate, washed with water, saturated NaCl solution, and ethyl acetate phase was dried over Na2SO4, filtered, concentrated and column purified to give desired product (106 mg). ESI (m/z): 306 (M+H)+.

Provenance & Evidence