Sodium Glycinate → HCID 54746582, compound

Participants

Reaction Steps

A mixture of 5-benzyloxy-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester (54 mg, 0.17 mmol) and sodium glycinate (241 mg, 2.48 mmol) in 2-methoxyethanol was refluxed for 18 h and then concentrated. Residue was dissolved in water (60 mL) and acidified using 1 N HCl to pH=3-4. Precipitate was collected, rinsed with water and dried in vacuo. Crude product was triturated with hexanes. Solid was collected and dried to provide the title compound (45 mg). MS ESI(+) m/e: 370.13 (M+1).

Provenance & Evidence