L-Alanine → HCID 54746587, compound

HRID 2190940Notes

Reaction equation

HRID 2190940 reaction equation
CO[C:3]([C:5]1[C:6](=[O:24])[O:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[C:10]([O:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH:9]=2)=[O:4].[NH2:25][C@H:26]([C:28]([OH:30])=[O:29])[CH3:27]>>[CH2:17]([O:16][C:10]1[CH:9]=[C:8]2[C:13]([C:14]([OH:15])=[C:5]([C:3]([NH:25][C@@H:26]([CH3:27])[C:28]([OH:30])=[O:29])=[O:4])[C:6](=[O:24])[O:7]2)=[CH:12][CH:11]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 5950L-AlanineHCID 86649473HCID 86649473, compound

Product 1

HCID 54746587HCID 54746587, compound

Procedure

2-(S)-[(7-Benzyloxy-4-hydroxy-2-oxo-2H-chromene-3-carbonyl)-amino]-propionic acid was prepared from 7-benzyloxy-4-hydroxy-2-oxo-2H-chromene-3-carboxylic acid methyl ester and L-alanine under conditions analogous to example 49-a. MS ESI(−) m/e: 382.03 (M−1).

Sources & evidence

ORD record
ord-14836dd37f3e441a9261244bcf2153f2
Source dataset
uspto-grants-2012_12
Patent number
US08324405B2

Reaction notes

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