HCID 68593032, compound → HCID 68594064, compound

Participants

Reaction Steps

Compound 6.6 (50 mg, 0.11 mmol) was dissolved in 15 mL NH4OH and stirred under N2 for overnight. The mixture was concentrated under reduced pressure. The residue was subjected to reverse phase HPLC eluting with 0-25% CH3CN in water to yield product 6.7 (34 mg, 89% yield). 1HNMR (300 MHz, D2O) δ 4.47-4.51 (m, 1H), 4.59-4.61 (m, 1H), 4.96-4.99 (m, 1H), 5.85 (t, 1H, J=17.1), 6.22-6.37 (m, 2H), 8.20 (s, 1H). 31P NMR: 10.98 ppm. LRMS (ESI) MH+ C10H13N6O6P requires 345.1. Found 345.8.

Provenance & Evidence