HCID 72247297, compound → HCID 72247367, compound

HRID 2191024Notes

Reaction equation

HRID 2191024 reaction equation
[C:1]([NH:9][C:10]1[CH:15]=[CH:14][N:13]([CH:16]2[O:20][CH:19]([CH:21]=[CH:22][P:23]([O:29]C(C)C)([O:25]C(C)C)=[O:24])[CH:18]([O:33][C:34](=[O:41])[C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)[CH:17]2[O:42][CH3:43])[C:12](=[O:44])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(NC1NC(=O)C2N=CN(C3OC(C=CP(O)(O)=O)C(OC(=O)C4C=CC=CC=4)C3OC)C=2N=1)(=O)C(C)C>>[C:1]([NH:9][C:10]1[CH:15]=[CH:14][N:13]([CH:16]2[O:20][CH:19]([CH:21]=[CH:22][P:23]([OH:29])([OH:25])=[O:24])[CH:18]([O:33][C:34](=[O:41])[C:35]3[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=3)[CH:17]2[O:42][CH3:43])[C:12](=[O:44])[N:11]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 72247297HCID 72247297, compoundHCID 136381450HCID 136381450, compound

Product 1

HCID 72247367HCID 72247367, compoundYield 49.6%

Procedure

Compound 17.4 (124 mg, 47.5% yield) was synthesized from compound 17.3 (300 mg, 0.462 mmol) using the procedure described for the preparation of compound 16.8.

Sources & evidence

ORD record
ord-a70d48d687694afcb868d8dd4a2547f4
Source dataset
uspto-grants-2012_12
Patent number
US08324179B2

Reaction notes

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