HCID 72247367, compound → HCID 68592118, compound

Participants

Reaction Steps

Compound 17.5 (37 mg, 95% yield) was synthesized from compound 17.4 (62 mg, 0.11 mmol) by treating 17.4 with concentrated NH4OH (10 ml) at 45° C. for 30 min. The reaction mixture was concentrated to dryness and purified by C-18 HPLC to afford compound 17.5. 1HNMR (D2O, 300 MHz) δ 7.65 (d, 1H), 6.29-6.45 (m, 1H), 5.96-6.10 (m, 3H), 5.85 (d, 1H), 4.42 (t, 1H), 4.10 (t, 1H), 3.91 (m, 1H), 3.40 (s, 3H), 31PNMR (D2O, 300 MHz): 0.90 ppm. LRMS [M−H]− C11H16N3O7P requires 332.1. Found 331.2.

Provenance & Evidence