HCID 135537371, compound → HCID 136381452, compound

HRID 2191026Notes

Reaction equation

HRID 2191026 reaction equation
O[CH2:2][CH:3]1[CH:7]2[O:8][C:9]([CH3:12])([CH3:11])[O:10][CH:6]2[CH:5]([N:13]2[CH:21]=[N:20][C:19]3[C:18](=[O:22])[NH:17][C:16]([NH:23][C:24](=[O:28])[CH:25]([CH3:27])[CH3:26])=[N:15][C:14]2=3)[O:4]1.[CH2:29]([O:31][P:32]([CH:37]=CC1C(OC(=O)C2C=CC=CC=2)C(OC)C(N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)O1)([O:34][CH2:35][CH3:36])=[O:33])[CH3:30]>>[CH2:29]([O:31][P:32]([CH:37]=[CH:2][CH:3]1[CH:7]2[CH:6]([O:10][C:9]([CH3:11])([CH3:12])[O:8]2)[CH:5]([N:13]2[CH:21]=[N:20][C:19]3[C:18](=[O:22])[NH:17][C:16]([NH:23][C:24](=[O:28])[CH:25]([CH3:26])[CH3:27])=[N:15][C:14]2=3)[O:4]1)(=[O:33])[O:34][CH2:35][CH3:36])[CH3:30]

Participants

3

Reactant 2

HCID 135537371HCID 135537371, compoundHCID 136381451HCID 136381451, compound

Product 1

HCID 136381452HCID 136381452, compoundYield 64%

Procedure

Compound 18.3 (1.7 g, 64% yield) was was synthesized from compound 18.2 (2.0 g, 5.09 mmol) using the procedure described for the preparation of compound 16.7.

Sources & evidence

ORD record
ord-0c3bed23e87046c9adc14b78b14cc14c
Source dataset
uspto-grants-2012_12
Patent number
US08324179B2

Reaction notes

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