HCID 136381450, compound → HCID 136381454, compound

HRID 2191028Notes

Reaction equation

HRID 2191028 reaction equation
C([O:3][P:4]([CH:9]=[CH:10][CH:11]1[CH:15]([OH:16])[CH:14]([OH:17])[CH:13]([N:18]2[CH:26]=[N:25][C:24]3[C:23](=[O:27])[NH:22][C:21]([NH:28][C:29](=[O:33])[CH:30]([CH3:32])[CH3:31])=[N:20][C:19]2=3)[O:12]1)(=[O:8])[O:5]CC)C.C(NC1NC(=O)C2N=CN(C3OC(C=CP(O)(O)=O)C(OC(=O)C4C=CC=CC=4)C3OC)C=2N=1)(=O)C(C)C>>[OH:16][CH:15]1[CH:14]([OH:17])[CH:13]([N:18]2[CH:26]=[N:25][C:24]3[C:23](=[O:27])[NH:22][C:21]([NH:28][C:29](=[O:33])[CH:30]([CH3:32])[CH3:31])=[N:20][C:19]2=3)[O:12][CH:11]1[CH:10]=[CH:9][P:4](=[O:3])([OH:5])[OH:8]

Participants

3

Reactant 2

HCID 136381450HCID 136381450, compoundHCID 136381453HCID 136381453, compound

Product 1

HCID 136381454HCID 136381454, compoundYield 67%

Procedure

Compound 18.5 (400 mg, 67% yield) was synthesized from compound 18.4 (680 mg, 1.4 mmol) using the procedure described for the preparation of compound 16.8.

Sources & evidence

ORD record
ord-f259fb3947124a5fbfa2851e2cadbf67
Source dataset
uspto-grants-2012_12
Patent number
US08324179B2

Reaction notes

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