HCID 86641131, compound → HCID 86641130, compound

HRID 2191061Notes

Reaction equation

HRID 2191061 reaction equation
[CH2:1]([O:3][P:4]([CH:9]=[CH:10][C:11]1([N:29]=[N+:30]=[N-:31])[CH:18]2[CH:14]([O:15]C(C)(C)[O:17]2)[CH:13]([N:21]2[CH:26]=[CH:25][C:24](=[O:27])[NH:23][C:22]2=[O:28])[O:12]1)(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2]>C(O)=O.O>[CH2:1]([O:3][P:4]([CH:9]=[CH:10][C:11]1([N:29]=[N+:30]=[N-:31])[CH:18]([OH:17])[CH:14]([OH:15])[CH:13]([N:21]2[CH:26]=[CH:25][C:24](=[O:27])[NH:23][C:22]2=[O:28])[O:12]1)(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2]

Participants

4

Reactant 1

HCID 86641131HCID 86641131, compound

Product 1

HCID 86641130HCID 86641130, compound

Reagents, catalysts & solvents 2

HCID 284Formic AcidSolventHCID 962WaterSolvent

Procedure

Compound 48.4 (130 mg, 0.29 mmol) was dissolved in 90% formic acid in water (2.8 mL). The solution was stirred at rt for 2 h and then concentrated under reduced pressure. The residue was used in the next step reaction without further purification.

Workup

  1. concentrationconcentrated under reduced pressure
  2. customThe residue was used in the next step reaction without further purification

Sources & evidence

ORD record
ord-93a5acaf10ba4204ab92db75bcaa26bb
Source dataset
uspto-grants-2012_12
Patent number
US08324179B2

Reaction notes

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