HCID 68429571, compound → HCID 68430118, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the compound obtained in step 1 (0.81 g), 20% Pd(OH)2/C (0.081 g) and methanol (10 mL) was stirred at 40° C. for 2 days under a hydrogen atmosphere. The insoluble material was removed by filtration, and the filtrate was concentrated under reduced pressure. The residue was purified by basic silica gel column chromatography (solvent gradient; 40→100% ethyl acetate/hexane) to give the title compound (0.16 g, 57%) as a colorless oil.

Provenance & Evidence