HCID 68430118, compound → HCID 68430491, compound

HRID 2191250Notes

Reaction equation

HRID 2191250 reaction equation
[C:1]([O:5][C:6]1[CH:7]=[CH:8][C:9]2[CH2:10][NH:11][CH2:12][CH2:13][O:14][C:15]=2[N:16]=1)([CH3:4])([CH3:3])[CH3:2].[C:17]([OH:24])(=[O:23])[CH2:18][CH2:19][C:20]([OH:22])=[O:21].CO>>[C:17]([OH:24])(=[O:23])[CH2:18][CH2:19][C:20]([OH:22])=[O:21].[C:1]([O:5][C:6]1[CH:7]=[CH:8][C:9]2[CH2:10][NH:11][CH2:12][CH2:13][O:14][C:15]=2[N:16]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 68430118HCID 68430118, compoundHCID 86640582HCID 86640582, compound

Product 1

HCID 68430491HCID 68430491, compoundYield 46%

Procedure

To the compound obtained in Example 1 (0.39 g) was added 0.5 M succinic acid/methanol solution (1.9 mL), and the solvent was evaporated under reduced pressure. The obtained residue was recrystallized from methanol-diethyl ether to give the title compound (0.27 g, 46%) as a white powder.

Workup

  1. customthe solvent was evaporated under reduced pressure
  2. customThe obtained residue was recrystallized from methanol-diethyl ether

Sources & evidence

ORD record
ord-c9209a4c52c54faeb0e02d74ee511cca
Source dataset
uspto-grants-2012_12
Patent number
US08329687B2

Reaction notes

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