HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dibromo-5-(trifluoromethoxy)benzene → HCID 10273358, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dibromo-5-(trifluoromethoxy)benzene | HCID 2761179 | — |
| Reactant | (4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid | HCID 10987806 | — |
| Product | HCID 10273358 | HCID 10273358 | — |
Reaction Steps
6-(3-Bromo-5-trifluoromethoxy-phenyl)-4,4-dimethyl-1,4-dihydrobenzo[d][1,3]-oxazin-2-one was prepared, using (4,4-dimethyl-1,4-dihydro-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid and 1,3-dibromo-5-trifluoromethoxybenzene according to the procedure of Example 5, as a white solid: mp 214-216° C.; 1H-NMR (DMSO-d6) δ 10.4 (s, 1H), 7.99 (s, 1H), 7.73 (s, 1H), 7.68-7.62 (m, 3H), 6.97 (d, 1H, J=8.0 Hz), 1.68 (s, 6H); MS (ESI) m/z 414 ([M−H]−, 100%); Anal. Calcd. For C17H13BrF3NO3: C, 49.06; H, 3.15; N, 3.37. Found: C, 49.16; H, 3.05; N, 3.30.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329690B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-eba2d1608fe2478b8b16e6b7cfd8a856 |
| Source note | uspto-grants-2012_12 |