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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2191599Generated: November 1, 2026

2,2-DiMethylcyclohexanaMine → HCID 54576053, compound

https://huagongshe.com/reaction/2191599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-DiMethylcyclohexanaMineHCID 14405857—
Reactant2-cyclopropyl-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acidHCID 57829653—
Reactant2-(1-ethyl-1H-pyrazol-4-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-b]pyrazine-7-carboxylic acidHCID 58438544—
ReactantHCID 67001422HCID 67001422—
ProductHCID 54576053HCID 54576053—

Reaction Steps

2-(1-Ethyl-1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (2,2-dimethyl-cyclohexyl)-amide was prepared according to the procedure outlined in Example 1, steps 4-5 substituting 2-(1-ethyl-1H-pyrazol-4-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-b]pyrazine-7-carboxylic acid for 2-cyclopropyl-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid and 2,2-dimethylcyclohexylamine [Example 21, steps 1-2] for 2-(1-amino-cyclopentyl)-propan-2-ol hydrochloride in step 4. MS: (M+H)+=367.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329699B2
Source datasetuspto-grants-2012_12
ORD IDord-fed50ea39b3c46a39ee9e8d78b9dd025
Source noteuspto-grants-2012_12