Acetic Acid → HCID 57667856, compound

Participants

Reaction Steps

A suspension of hydrazine monohydrate 5.0 mL of 2-(acetamido)-4-phenoxybenzoic acid 1.5 g was heated and refluxed for 4 hours. After the reaction mixture was cooled to room temperature, acetic acid 10 mL, ethyl acetate and saturated sodium chloride aqueous solution were added to it. The organic layer was separated and collected,dried over anhydrous magnesium sulfate, the solvent was removed under reduced pressure. Diisopropyl ether and hexane were added to the obtained residue, solid matter was filtrated to give 2-amino-4-phenoxybenzoic acid 1.2 g of white solid.

Provenance & Evidence