HCID 68960562, compound → HCID 57667902, compound

Participants

Reaction Steps

To methanol 2.0 mL solution of tert-butyl 4-(2-cyclopenten-1-yl)-2-(4-fluoroanilino)benzoate 45 mg was added 5% palladium-carbon 9 mg, and it was stirred under hydrogen atmosphere at room temperature for 6 hours. Insoluble matter was filtrated, and the solvent was removed under reduced pressure. Trifluoroacetic acid 10 mL was added to the obtained residue, and it was stirred at room temperature for 1 hour. The solvent was removed under reduced pressure, methanol was added to the obtained residue, and solid matter was filtrated to give 4-cyclopentyl-2-(4-fluoroanilino)benzoic acid 24 mg of white solid.

Provenance & Evidence