Hydrochloric Acid → HCID 57667855, compound

Participants

Reaction Steps

10% Sodium hydroxide aqueous solution 1.0 mL was added to a suspension of 2-propanol 2.0 mL of methyl 2-(4-fluoroanilino)-4-(phenylthio)benzoate 0.21 g at room temperature, and it was heated and refluxed for 2 hours. After the reaction mixture was cooled to room temperature, 1.0 mol/L hydrochloric acid and ethyl acetate were added to it. The organic layer was separated and collected,dried over anhydrous magnesium sulfate, the solvent was removed under reduced pressure to give 2-(4-fluoroanilino)-4-(phenylthio)benzoic acid 0.16 g of pale yellow solid.

Provenance & Evidence