Tert-butyl 2-(4-morpholinoanilino)-4-phenylbenzoate → 2-(4-Morpholinoanilino)-4-phenylbenzoic acid

関与物質

反応手順

Trifluoroacetic acid 10 mL was added to the obtained tert-butyl 2-(4-morpholinoanilino)-4-phenylbenzoate, and it was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure, the obtained residue was refined by reversed-phase silica gel column chromatography [eluent; 50-80% acetonitrile/0.1% trifluoroacetic acid aqueous solution] to give 2-(4-morpholinoanilino)-4-phenylbenzoic acid 31 mg of a yellow solid.

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