HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tert-butyl 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoate → 2-((Benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tert-butyl 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoate | HCID 68960417 | — |
| Lösungsmittel | Trifluoroacetic acid | HCID 6422 | — |
| Produkt | 2-((Benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoic acid | HCID 57668046 | — |
Reaktionsschritte
Trifluoroacetic acid 10 mL was added to the obtained tert-butyl 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoate, and it was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure, methanol was added to the obtained residue, and solid matter was filtrated to give 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoic acid 67 mg of a brown solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08327467B2 |
| Quelldatensatz | uspto-grants-2012_12 |
| ORD ID | ord-fc2f9069e44d455395a314d79d6a76a2 |
| Quellennotiz | uspto-grants-2012_12 |