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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2191828Erstellt: 25. Oktober 2026

Tert-butyl 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoate → 2-((Benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoic acid

https://huagongshe.com/reaction/2191828

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTert-butyl 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoateHCID 68960417—
LösungsmittelTrifluoroacetic acidHCID 6422—
Produkt2-((Benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoic acidHCID 57668046—

Reaktionsschritte

Trifluoroacetic acid 10 mL was added to the obtained tert-butyl 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoate, and it was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure, methanol was added to the obtained residue, and solid matter was filtrated to give 2-((benzothiophen-5-yl)amino)-4-(indolin-1-yl)benzoic acid 67 mg of a brown solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08327467B2
Quelldatensatzuspto-grants-2012_12
ORD IDord-fc2f9069e44d455395a314d79d6a76a2
Quellennotizuspto-grants-2012_12