HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-methylphenyl Isocyanate → HCID 58329448, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-methylphenyl Isocyanate | HCID 4093965 | — |
| Reactant | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| Product | HCID 58329448 | HCID 58329448 | 59.6% |
Reaction Steps
1-Cyclopentyl-3-(4-fluoro-3-methyl-phenyl)-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione (25 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 1-fluoro-4-isocyanato-2-methyl-benzene (0.5 mmol) following general procedure C. LCMS: m/z 420 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329715B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-3522ed0dc3d14424a5cce45b244a52ac |
| Source note | uspto-grants-2012_12 |