HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 1-Acetylindolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Oxindole | HCID 321710 | — |
| Product | 1-Acetylindolin-2-one | HCID 323719 | 93.7% |
Reaction Steps
Indoline-2-one (6.65 g, 50 mmol) and acetic anhydride (9 mL) were heated at reflux for 15 h. After cooling, the product was filtered and rinsed with Et2O to give 2a as solids after vacuum drying (8.2 g, yield: 93.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329718B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-2e808d025c2448a0847dfb4f94349b47 |
| Source note | uspto-grants-2012_12 |