3,3-Dimethyl-1-(2-nitrophenyl)-2,3-dihydro-1H-indole → 2-(3,3-Dimethyl-2,3-dihydro-1H-indol-1-yl)aniline

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Reaction Steps

To a solution of 2d (123 mg, 0.458 mmol) in MeOH was added 10% Pd/C (20 mg). The reaction mixture was stirred at rt under H2 for 2 h. The catalyst was filtered through a cake of Celite® and the filtrate was evaporated under reduced pressure to afford 2e (80 mg, 75%) as a yellowish powder. MS (ES) m/z 239 [M+H]+.

Provenance & Evidence