HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine hydrochloride → 6-(3-bromo-6-(4-methoxyphenyl)-1H-indol-1-yl)-N-methylpyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine hydrochloride | HCID 6364545 | — |
| Reactant | 3-bromo-1-(6-chloropyrimidin-4-yl)-6-(4-methoxyphenyl)-1H-indole | HCID 50991546 | — |
| Product | 6-(3-bromo-6-(4-methoxyphenyl)-1H-indol-1-yl)-N-methylpyrimidin-4-amine | HCID 50991547 | — |
Reaction Steps
The target compound was prepared as in Example 10 using 3-bromo-1-(6-chloropyrimidin-4-yl)-6-(4-methoxyphenyl)-1H-indole (400 mg, 0.96 mmol) and methylamine hydrochloride (326 mg, 4.8 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329708B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-a330055f2a7c449e9e77d628ddb61f05 |
| Source note | uspto-grants-2012_12 |