2-Fluorobenzoic acid → 2-(2,3-Difluorophenyl)-3H-imidazo[4,5-c]pyridine

HRID 2192290Notes

Reaction equation

HRID 2192290 reaction equation
[F:1]C1C=CC=CC=1C(O)=O.[F:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:18]1[NH:26][C:21]2[CH:22]=[N:23][CH:24]=[CH:25][C:20]=2[N:19]=1>>[F:11][C:12]1[C:17]([F:1])=[CH:16][CH:15]=[CH:14][C:13]=1[C:18]1[NH:26][C:21]2[CH:22]=[N:23][CH:24]=[CH:25][C:20]=2[N:19]=1

Participants

3

Reactant 2

HCID 99352-Fluorobenzoic acidHCID 134507782-(2-Fluorophenyl)-3H-imidazo[4,5-c]pyridine

Product 1

HCID 272821652-(2,3-Difluorophenyl)-3H-imidazo[4,5-c]pyridine

Procedure

Following the above taught procedure and substituting 2-fluorobenzoic acid in place of 2,3-difluorobenzoic acid, the compound 2-(2-fluorophenyl)-3H-imidazo[4,5-c]pyridine can be prepared.

Sources & evidence

ORD record
ord-4b3d96e286a84925a09fee7327bf6532
Source dataset
uspto-grants-2012_12
Patent number
US08329727B2

Reaction notes

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