HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpentane → HCID 86655271, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpentane | HCID 7892 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Bromo-N-(3-methylisoxazol-5-yl)acetamide | HCID 13362964 | — |
| Reactant | HCID 58348375 | HCID 58348375 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86655271 | HCID 86655271 | 45.8% |
Reaction Steps
1-Thiophen-2-yl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (Example 5d) (50 mg) and 2-bromo-N-(3-methylisoxazol-5-yl)acetamide (Example 7a) (32 mg) were dissolved in acetonitrile (2 mL) and left overnight. Ethyl acetate (10 mL) and isohexane (10 mL) were added and the crystals filtered off, washed with ethyl acetate and dried to afford the titled compound (37 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329729B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-85ed8045569a4562a5af4971a8928d67 |
| Source note | uspto-grants-2012_12 |