Diethyl Ether → HCID 86655279, compound

Participants

Reaction Steps

2-Chloro-N-(5-fluoro-pyridin-2-yl)-acetamide (Example 17a) (31 mg) was added to a solution of 1-phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (Example 14e) (49 mg) in acetonitrile (1 mL). The reaction mixture was stirred at room temperature overnight. Diethyl ether (2 mL) was added to the reaction mixture and the white solid was filtered off, washed several times with diethyl ether and dried under vacuum at 40° C. to give the title compound (49 mg).

Provenance & Evidence