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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2192370Generated: November 1, 2026

2-Chloro-N-(4-methylpyridin-2-yl)acetamide → HCID 53311263, compound

https://huagongshe.com/reaction/2192370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-N-(4-methylpyridin-2-yl)acetamideHCID 2776797—
Reactant1-Phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)esterHCID 59179619—
SolventAcetonitrileHCID 6342—
ProductHCID 53311263HCID 5331126351.2%

Reaction Steps

To a solution of 1-phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3yl) ester (Example 14e) (100 mg) in 1 mL MeCN was added 2-chloro-N-(4-methyl-pyridin-2-yl)-acetamide (Example 44a) (62 mg) and the mixture was stirred at room temperature for 21 h. The precipitate was filtered off and dried under vacuum at 50° C. to give the title compound (80 mg) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329729B2
Source datasetuspto-grants-2012_12
ORD IDord-cbc8ad22c72b41c6bd36c586b1d76aaa
Source noteuspto-grants-2012_12