2-Bromo-N-(4-methylphenyl)acetamide → HCID 86655289, compound

Participants

Reaction Steps

To 1-phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (Example 14e) (51 mg) in acetonitrile (1 mL) was added 2-bromo-N-p-tolyl-acetamide (Example 46a) (39 mg). The reaction was stirred at room temperature overnight and the acetonitrile was removed under reduced pressure. The material was recrystallised from acetonitrile/ethyl acetate to afford the title compound as a colourless solid (16 mg).

Provenance & Evidence