HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22887946, compound → HCID 86655304, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22887946 | HCID 22887946 | — |
| Reactant | 1-Phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester | HCID 59179619 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86655304 | HCID 86655304 | 19.8% |
Reaction Steps
1-phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester (Example 14e) (0.30 mmol) and 2-chloro-N-[1,2,4]thiadiazol-5-yl-acetamide (0.36 mmol) (Example 56a) in MeCN (1.5 mL) were stirred at room temperature overnight. The reaction mixture was filtered and the solid obtained was washed with cold MeCN to give the title compound (30 mg) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329729B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-b1aea704fef34fbfb30629ae3195819d |
| Source note | uspto-grants-2012_12 |