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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2192391Generated: November 2, 2026

HCID 22887946, compound → HCID 86655304, compound

https://huagongshe.com/reaction/2192391

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22887946HCID 22887946—
Reactant1-Phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)esterHCID 59179619—
SolventAcetonitrileHCID 6342—
ProductHCID 86655304HCID 8665530419.8%

Reaction Steps

1-phenyl-cycloheptanecarboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester (Example 14e) (0.30 mmol) and 2-chloro-N-[1,2,4]thiadiazol-5-yl-acetamide (0.36 mmol) (Example 56a) in MeCN (1.5 mL) were stirred at room temperature overnight. The reaction mixture was filtered and the solid obtained was washed with cold MeCN to give the title compound (30 mg) as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329729B2
Source datasetuspto-grants-2012_12
ORD IDord-b1aea704fef34fbfb30629ae3195819d
Source noteuspto-grants-2012_12