HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluorophenylboronic acid → HCID 46313864, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluorophenylboronic acid | HCID 2734354 | — |
| Reactant | 6-Bromo-5-fluoropicolinic Acid | HCID 53401194 | — |
| Catalyst | HCID 178418807 | HCID 178418807 | — |
| Product | HCID 46313864 | HCID 46313864 | 43% |
Reaction Steps
Method 1 was followed using 6-bromo-5-fluoropicolinic acid (1.0 equiv.) and 2-fluorophenylboronic acid (1.3 equiv.) and Pd(dppf)Cl2-DCM (0.05 equiv.) to give 5-fluoro-6-(2-fluorophenyl)picolinic acid in 43% yield. LC/MS=236.1 (M+H), Rt=0.72 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329732B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-60f67c891d094e3d952abb009756eb94 |
| Source note | uspto-grants-2012_12 |