HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyclohexenylboronic acid → HCID 59226617, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyclohexenylboronic acid | HCID 3862902 | — |
| Reactant | 6-Bromo-5-fluoropicolinic Acid | HCID 53401194 | — |
| Catalyst | HCID 178418807 | HCID 178418807 | — |
| Product | HCID 59226617 | HCID 59226617 | 61% |
Reaction Steps
Method 1 was followed using 6-bromo-5-fluoropicolinic acid (1.0 equiv.) and cyclohexenylboronic acid (1.3 equiv.) and Pd(dppf)Cl2-DCM (0.15 equiv.) to give 6-cyclohexenyl-5-fluoropicolinic acid in 61% yield. LC/MS=222.0 (M+H), Rt=0.52 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329732B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-fc5b06c73baf4b1fbf410323251a68be |
| Source note | uspto-grants-2012_12 |