HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59226617, compound → HCID 59226414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59226617 | HCID 59226617 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59226414 | HCID 59226414 | 65% |
Reaction Steps
To a degassed solution of 6-cyclohexenyl-5-fluoropicolinic acid (1.0 equiv.) in MeOH (0.07M) was added 10% Pd/C (0.1 equiv.) and the reaction was stirred under a hydrogen balloon overnight. The solution was then filtered, rinsed with MeOH, and the filtrate was concentrated to afford 6-cyclohexyl-5-fluoropicolinic acid in 65% yield. LC/MS=224.2 (M+H), Rt=0.95 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329732B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-04b6d2e77c884a06bfe4aa6b155dfbc4 |
| Source note | uspto-grants-2012_12 |