4-Hydroxy-1-[(4-nitrophenyl)methyl]-1H-imidazole-5-carboxamide → HCID 25029752, compound

Participants

Reaction Steps

1 g (3.81 mmol) of 3-(4-nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide is placed in 30 ml of methanol with 100 mg of palladium-on-charcoal (51% water) in a hydrogenation flask. The medium is flushed with argon and then with hydrogen for 30 minutes with stirring. The medium is again flushed with argon and the catalyst is filtered off by suction. The solvent is evaporated off to give 0.710 g of a yellowish-white solid.

Provenance & Evidence