化工社化工社 化学情報印刷レポート · 研究参考用
Isoxazolidine hydrochloride → 3-(4-Chloro-2-hydroxy-3-(isoxazolidin-2-ylsulfonyl)phenylamino)-4-ethoxycyclobut-3-ene-1,2-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isoxazolidine hydrochloride | HCID 12304500 | — |
| 反応物 | Ethyl(methoxy)amine hydrochloride | HCID 22613948 | — |
| 反応物 | 6-Chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-ethyl-benzenesulfonamide | HCID 86638631 | — |
| 生成物 | 3-(4-Chloro-2-hydroxy-3-(isoxazolidin-2-ylsulfonyl)phenylamino)-4-ethoxycyclobut-3-ene-1,2-dione | HCID 86658404 | — |
反応手順
This compound was prepared analogously to 6-chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-ethyl-benzenesulfonamide (Intermediate FA) by replacing N-ethyl-O-methylhydroxylamine hydrochloride (Intermediate G) with isoxazolidine hydrochloride. [M+H]+ 402.9
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08329754B2 |
| 出典データセット | uspto-grants-2012_12 |
| ORD ID | ord-d6a8b838e56d4b559457c65f763bdbcc |
| 出典メモ | uspto-grants-2012_12 |