HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen chloride-ethyl acetate → HCID 68434155, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | HCID 59625389 | HCID 59625389 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68434155 | HCID 68434155 | — |
Reaction Steps
tert-Butyl (3S,5R)-3-[({2-tert-butyl-4-[(3-methoxypropyl)amino]pyrimidin-5-yl}carbonyl)(2-methylpropyl)amino]-5-[(4-methylpiperazin-1-yl)carbonyl]piperidine-1-carboxylate (87 mg) was dissolved in ethyl acetate (1 ml), 4 N hydrogen chloride-ethyl acetate solution (1 ml) was added, and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated under reduced pressure, and the residue was dried under reduced pressure to give the object compound (87 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329691B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-39b029a75f3a42b4890241dea516554e |
| Source note | uspto-grants-2012_12 |