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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2192877Generated: October 31, 2026

Hydrogen chloride-ethyl acetate → HCID 68434155, compound

https://huagongshe.com/reaction/2192877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen chloride-ethyl acetateHCID 21866389—
ReactantHCID 59625389HCID 59625389—
SolventEthyl AcetateHCID 8857—
ProductHCID 68434155HCID 68434155—

Reaction Steps

tert-Butyl (3S,5R)-3-[({2-tert-butyl-4-[(3-methoxypropyl)amino]pyrimidin-5-yl}carbonyl)(2-methylpropyl)amino]-5-[(4-methylpiperazin-1-yl)carbonyl]piperidine-1-carboxylate (87 mg) was dissolved in ethyl acetate (1 ml), 4 N hydrogen chloride-ethyl acetate solution (1 ml) was added, and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated under reduced pressure, and the residue was dried under reduced pressure to give the object compound (87 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329691B2
Source datasetuspto-grants-2012_12
ORD IDord-39b029a75f3a42b4890241dea516554e
Source noteuspto-grants-2012_12