反应详情

温度

40 °C

To 45 mL of an ethanol solution containing 0.8 g of N-(2-(1,4-dioxaspiro(4.5)decan-8-yl)ethyl)-5-methoxy-2-nitroaniline, 0.25 g of 10% palladium-carbon was added at room temperature, and the mixture was stirred at 40° C. for 3 hours and 30 minutes under a hydrogen atmosphere. The insoluble material filtered off, and the solvent was removed under reduced pressure to obtain 0.81 g of a violet oily substance, 2-(2-(1,4-dioxaspiro(4.5)decan-8-yl)ethyl)amino-4-methoxyaniline.

1. additionwas added at room temperature
2. filtrationThe insoluble material filtered off
3. customthe solvent was removed under reduced pressure