Ethylamine → HCID 67274438, compound

HRID 2193538Notes

Reaction equation

HRID 2193538 reaction equation
[C:1]1([CH2:7][N:8]2[CH2:13][CH2:12][N:11]([CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:10][CH:9]2[CH:21]=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:23]([NH2:25])[CH3:24]>ClCCl>[CH2:7]([N:8]1[CH2:13][CH2:12][N:11]([CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:10][CH:9]1[CH:21]=[N:25][CH2:23][CH3:24])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 6341EthylamineHCID 154809991,4-Dibenzylpiperazine-2-carbaldehyde

Product 1

HCID 67274438HCID 67274438, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 0.5 g (1,4-bis(phenylmethyl)-2-piperazin-carboxaldehyde in 5 ml of dichloromethane was added 0.54 ml ethylamine and 0.5 g molecular sieves. The reaction mixture was stirred for 30 min at rt then filtered. The filtrate was evaporated to dryness.

Workup

  1. filtrationthen filtered
  2. customThe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-4768627adb034e5dba895faf09162926
Source dataset
uspto-grants-2012_12
Patent number
US08329908B2

Reaction notes

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