HCID 67274379, compound → HCID 67274078, compound

Participants

Reaction Steps

A suspension of 500 mg of 10% Pd/C and 2.5 g 4-(4-{4-[(5R)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-piperazin-1-yl)-piperidin-1-carboxylic acid benzyl ester(, 5.51 mmol) in 50 ml methanol was stirred under hydrogen. The reaction was monitored by TLC. The Pd/C was filtered off, the filtrate evaporated to dryness and the residue digested in an ethyl acetate/hexane mixture. The glassy solid was filtered, washed with hexane and dried.

Provenance & Evidence