HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 2-Ethoxy-5-(2-pyridyl)phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | 5-(5-Bromo-2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-D]pyrimidin-7(6H)-one | HCID 135738554 | — |
| Product | 2-Ethoxy-5-(2-pyridyl)phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one | HCID 135749781 | — |
Reaction Steps
The title compound was prepared from 2-bromopyridine and 5-(5-bromo-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, following the procedure described in Example 32, and was obtained as an off-white solid (33%), m.p. 216°-218° C. Found: C,67.71; H,5.81; N,17.63. C22H23N5O2 requires C,67.85; H,5.95; N,17.98%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05426107 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-06d6616fa021449d8371a1195c42430b |
| Source note | uspto-grants-1995_06 |