4-Ethylaniline → HCID 49801069, compound

HRID 2194018Notes

Reaction equation

HRID 2194018 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][CH:17]([CH3:23])[CH2:18][S:19](Cl)(=[O:21])=[O:20].[CH2:24]([C:26]1[CH:32]=[CH:31][C:29]([NH2:30])=[CH:28][CH:27]=1)[CH3:25]>>[CH2:24]([C:26]1[CH:32]=[CH:31][C:29]([N:30]2[CH2:13][CH2:12][C:6]3([CH2:7][CH2:8][N:9]([S:19]([CH2:18][CH:17]([CH3:23])[CH3:16])(=[O:21])=[O:20])[CH2:10][CH2:11]3)[C:4]2=[O:5])=[CH:28][CH:27]=1)[CH3:25]

Participants

4

Reactant 3

HCID 115044-EthylanilineHCID 1822361-Propanesulfonyl chloride, 2-methyl-HCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49801069HCID 49801069, compound

Procedure

Off-white solid. MS (ESI): 379.20 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-methyl-propane-1-sulfonyl chloride and 4-ethylaniline.

Sources & evidence

ORD record
ord-98616207e4f746689457b78553c7a5c5
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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