4-Propylaniline → HCID 49801352, compound

HRID 2194022Notes

Reaction equation

HRID 2194022 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][C:17]([CH3:23])([CH3:22])[CH2:18][C:19](Cl)=[O:20].[CH2:24]([C:27]1[CH:33]=[CH:32][C:30]([NH2:31])=[CH:29][CH:28]=1)[CH2:25][CH3:26]>>[CH3:16][C:17]([CH3:23])([CH3:22])[CH2:18][C:19]([N:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:31]([C:30]3[CH:32]=[CH:33][C:27]([CH2:24][CH2:25][CH3:26])=[CH:28][CH:29]=3)[CH2:13][CH2:12]2)[CH2:11][CH2:10]1)=[O:20]

Participants

4

Reactant 3

HCID 759084-PropylanilineHCID 815143,3-Dimethylbutanoyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49801352HCID 49801352, compound

Procedure

Off-white solid. MS (ESI): 371.26 (MH+). This example was prepared in analogy to example 7 step A) to B) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 3,3-dimethyl-butyryl chloride and 4-propyl-aniline.

Sources & evidence

ORD record
ord-a2051b5280a5427ab7f28b4ace1baabc
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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