Cyclopentylacetyl chloride → HCID 49802796, compound

HRID 2194028Notes

Reaction equation

HRID 2194028 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH:16]1([CH2:21][C:22](Cl)=[O:23])[CH2:20][CH2:19][CH2:18][CH2:17]1.[CH:25]1([C:28]2[CH:34]=[CH:33][C:31]([NH2:32])=[CH:30][CH:29]=2)[CH2:27][CH2:26]1>>[CH:16]1([CH2:21][C:22]([N:9]2[CH2:8][CH2:7][C:6]3([C:4](=[O:5])[N:32]([C:31]4[CH:33]=[CH:34][C:28]([CH:25]5[CH2:27][CH2:26]5)=[CH:29][CH:30]=4)[CH2:13][CH2:12]3)[CH2:11][CH2:10]2)=[O:23])[CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

4

Reactant 3

HCID 3485182Cyclopentylacetyl chlorideHCID 122539274-CyclopropylanilineHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49802796HCID 49802796, compound

Procedure

Off-white solid. MS (ESI): 381.25 (MH+). This example was prepared in analogy to example 7 step A) to B) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), cyclopentylacetyl chloride and 4-cyclopropyl-aniline.

Sources & evidence

ORD record
ord-1ca10d6ff16d4588962c357a1e7ca267
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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