4-Ethylaniline → HCID 49803068, compound

HRID 2194032Notes

Reaction equation

HRID 2194032 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][C:17]1[S:21][C:20]([S:22](Cl)(=[O:24])=[O:23])=[CH:19][CH:18]=1.[CH2:26]([C:28]1[CH:34]=[CH:33][C:31]([NH2:32])=[CH:30][CH:29]=1)[CH3:27]>>[CH2:26]([C:28]1[CH:34]=[CH:33][C:31]([N:32]2[CH2:13][CH2:12][C:6]3([CH2:7][CH2:8][N:9]([S:22]([C:20]4[S:21][C:17]([CH3:16])=[CH:18][CH:19]=4)(=[O:24])=[O:23])[CH2:10][CH2:11]3)[C:4]2=[O:5])=[CH:30][CH:29]=1)[CH3:27]

Participants

4

Reactant 3

HCID 115044-EthylanilineHCID 124001125-Methylthiophene-2-sulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49803068HCID 49803068, compound

Procedure

Off-white solid. MS (ESI): 419.14 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 5-methylthiophene-2-sulphonyl chloride and 4-ethyl-aniline.

Sources & evidence

ORD record
ord-ce3da2132318465ebadc32eed574aee8
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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