Benzenamine, 4-(1-methylpropyl)- → HCID 49803072, compound

HRID 2194036Notes

Reaction equation

HRID 2194036 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][C:17]1[S:21][C:20]([S:22](Cl)(=[O:24])=[O:23])=[CH:19][CH:18]=1.[CH:26]([C:30]1[CH:35]=[CH:34][C:33]([NH2:36])=[CH:32][CH:31]=1)([CH2:28][CH3:29])[CH3:27]>>[CH:26]([C:30]1[CH:31]=[CH:32][C:33]([N:36]2[CH2:13][CH2:12][C:6]3([CH2:7][CH2:8][N:9]([S:22]([C:20]4[S:21][C:17]([CH3:16])=[CH:18][CH:19]=4)(=[O:24])=[O:23])[CH2:10][CH2:11]3)[C:4]2=[O:5])=[CH:34][CH:35]=1)([CH2:28][CH3:29])[CH3:27]

Participants

4

Reactant 3

HCID 121771Benzenamine, 4-(1-methylpropyl)-HCID 124001125-Methylthiophene-2-sulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49803072HCID 49803072, compound

Procedure

Off-white solid. MS (ESI): 447.17 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 5-methylthiophene-2-sulphonyl chloride and 4-sec-butyl-phenylamine.

Sources & evidence

ORD record
ord-46447d09b45c4597bb20805081efa90e
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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