4-Ethylaniline → HCID 49803346, compound

HRID 2194042Notes

Reaction equation

HRID 2194042 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][S:17]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[S:26](Cl)(=[O:28])=[O:27])(=[O:19])=[O:18].[CH2:30]([C:32]1[CH:38]=[CH:37][C:35]([NH2:36])=[CH:34][CH:33]=1)[CH3:31]>>[CH2:30]([C:32]1[CH:38]=[CH:37][C:35]([N:36]2[CH2:13][CH2:12][C:6]3([CH2:7][CH2:8][N:9]([S:26]([C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=4[S:17]([CH3:16])(=[O:19])=[O:18])(=[O:28])=[O:27])[CH2:10][CH2:11]3)[C:4]2=[O:5])=[CH:34][CH:33]=1)[CH3:31]

Participants

4

Reactant 3

HCID 115044-EthylanilineHCID 27351782-Methanesulfonylbenzene-1-sulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49803346HCID 49803346, compound

Procedure

Off-white solid. MS (ESI): 413.20 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-methanesulfonyl-benzenesulfonyl chloride and 4-ethylaniline.

Sources & evidence

ORD record
ord-9dbe96b29d024a7e94468e86782eed88
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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