4-Propylaniline → HCID 49803636, compound

HRID 2194047Notes

Reaction equation

HRID 2194047 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][S:17]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[S:26](Cl)(=[O:28])=[O:27])(=[O:19])=[O:18].[CH2:30]([C:33]1[CH:39]=[CH:38][C:36]([NH2:37])=[CH:35][CH:34]=1)[CH2:31][CH3:32]>>[CH3:16][S:17]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[S:26]([N:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:37]([C:36]3[CH:38]=[CH:39][C:33]([CH2:30][CH2:31][CH3:32])=[CH:34][CH:35]=3)[CH2:13][CH2:12]2)[CH2:11][CH2:10]1)(=[O:28])=[O:27])(=[O:19])=[O:18]

Participants

4

Reactant 3

HCID 759084-PropylanilineHCID 27351782-Methanesulfonylbenzene-1-sulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49803636HCID 49803636, compound

Procedure

White solid. MS (ESI): 491.16 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-methanesulfonyl-benzenesulfonyl chloride and 4-propyl-aniline.

Sources & evidence

ORD record
ord-9507bd8988ae4e9e8d99b61e398e4a89
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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