1-Propanesulfonyl chloride, 2-methyl- → HCID 49804218, compound

HRID 2194054Notes

Reaction equation

HRID 2194054 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH3:16][CH:17]([CH3:23])[CH2:18][S:19](Cl)(=[O:21])=[O:20].[CH:24]1([O:29][C:30]2[CH:36]=[CH:35][C:33]([NH2:34])=[CH:32][CH:31]=2)[CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH:24]1([O:29][C:30]2[CH:31]=[CH:32][C:33]([N:34]3[CH2:13][CH2:12][C:6]4([CH2:7][CH2:8][N:9]([S:19]([CH2:18][CH:17]([CH3:23])[CH3:16])(=[O:21])=[O:20])[CH2:10][CH2:11]4)[C:4]3=[O:5])=[CH:35][CH:36]=2)[CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

4

Reactant 3

HCID 1822361-Propanesulfonyl chloride, 2-methyl-HCID 64844484-(cyclopentyloxy)anilineHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49804218HCID 49804218, compound

Procedure

Pink solid. MS (ESI): 435.23 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-methyl-propane-1-sulfonyl chloride and 4-(cylopentyloxy)-aniline.

Sources & evidence

ORD record
ord-3ce89afe51924fb381c80d350e404fd1
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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